Wolfram Syndrome Clinic Program

At the Washington University Medical Center’s Center for Advanced Medicine, we have established the Wolfram Syndrome Clinic program, aimed at improving clinical care for patients with Wolfram syndrome and related disorders, including WFS1-related deafness and optic nerve atrophy.

Our program provides genetic evaluations, education, and counseling services to patients and family members of all ages who have either been diagnosed with Wolfram syndrome, are suspected of having it, or have WFS1-related disorders.

Our team collaborates with other specialists, including neurologists, neuro-ophthalmologists, urologists, medical geneticists, and endocrinologists at our medical center, to provide personalized management plans. We strive to see patients either on the same day or within two consecutive days. Our services are available to both pediatric and adult patients.

Schedule an Appointment with our Wolfram Syndrome Clinic:

Patients in Missouri

If you’re in Missouri, please call Christine Manning, RN, Nurse Coordinator, at 314-747-7055 or 314-362-3500.

Let her know that you or your family member has Wolfram syndrome or WFS1-related medical conditions and need to make an appointment. Once we review your medical records, Dr. Urano or his staff will contact you to discuss which specialists you may need to see.

Sending Medical Records via Fax

Please fax your medical records to 314-747-7065.

Referrals via Fax for both Missouri patients and out-of-state patients

Please fax your referral request to 314-747-7065.

Out-of-State Patients

If you’re out of state, please call Christine Manning, RN, Nurse Coordinator, at 314-747-7055 or 314-362-3500.

Let her know that you or your family member have Wolfram syndrome or WFS1-related medical conditions and need to make an appointment. Once we review your medical records, Dr. Urano or his staff will contact you to discuss which specialists you may need to see.

Sending Medical Records via Fax

Please fax your medical records to 314-747-7065.

Referrals via Fax for both Missouri patients and out-of-state patients

Please fax your referral request to 314-747-7065.

International Patients

International patients are welcome to contact our international patient care office to schedule an appointment by calling +1-314-273-3780 or sending an email to Internationalpatients@wustl.edu.

Sending Medical Records via Fax

Please fax your medical records to 314-747-7065.

Referrals via Fax for both Missouri patients and out-of-state patients

Please fax your referral request to 314-747-7065.

Additional Physicians

All of the the following physicians are collaborators of the Wolfram Syndrome Clinic.


Interested in Research Studies

If you’re interested in participating in clinical research studies related to Wolfram syndrome, you can get in touch with our research nurse coordinator, Stacy Hurst, RN, CDE, by calling 314-747-3294 or sending an email to shurst@wustl.edu.

Washington University Medical Center is recognized as a Rare Disease Center of Excellence, with excellent specialists committed to providing exceptional care.