Research Research ClinicIn September of 2009 we established the Internet-based International Wolfram Syndrome Registry. As the prevalence is estimated at 1 in 200,000-700,000, the Registry was established to provide a cohort of patients for future studies. Urano LabWelcome to the Urano lab website at the Washington University School of Medicine. The ultimate goal of our research is to find a cure for Wolfram syndrome, a prototype endoplasmic reticulum disease. Request MaterialsThank you for your interest in our research and reagents. We make all possible efforts to make available the published reagents generated in our lab.