We are looking for soluble factors in our body that can enhance the regeneration of damaged tissues in Wolfram syndrome and Type 1 diabetes. We have discovered two molecules so far. One of them is MANF.
We are trying to produce a large amount of these factors in the dish (recombinant proteins) and give these factors to animal models and cell models. We are also looking for methods/small molecules (i.e., drugs) to enhance the functions of these factors. This strategy is also related to “regenerative therapy”, but independent of stem cells.
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