Try and try and try again

I appreciate my teams’ multiple efforts to develop novel treatment for Wolfram syndrome. A dose-escalation study for dantrolene is ongoing. We are developing AAV-based gene therapy, new drug screening methods, genome-editing-based therapy, and stem-cell therapy. At the same time, I need to secure funds for clinical trials. For each effort, there are obstacles, but I will try and try and try again to make these work.

I have three things always on my mind.

1. A cure for Wolfram syndrome

2. Provide better clinical care for Wolfram syndrome

3. Raise awareness of Wolfram syndrome

Again, for accomplishing each aim, there are many roadblocks to overcome. I sometimes want to cry out for help, but I will try and try and try again.

Thank you for your support and encouragement. I appreciate it from the bottom of my heart.


Fumi Urano